These total results cannot be extrapolated to various other intermittent-treatment schedules or disease characteristics.. Juanita M. Crook, M.D., Christopher J. O’Callaghan, D.V.M., Ph.D., Graeme Duncan, M.D., David P. Dearnaley, M.D., Celestia S. Higano, M.D., Eric M. Horwitz, M.D., Eliot Frymire, M.A., Shawn Malone, M.D., Joseph Chin, M.D., Abdenour Nabid, M.D., Padraig Warde, M.B., Thomas Corbett, M.D., Steve Angyalfi, M.D., S. Larry Goldenberg, M.D., Mary K. Gospodarowicz, M.D., Fred Saad, M.D., John P. Logue, M.R.C.P., Emma Hall, Ph.D., Paul F. Schellhammer, M.D., Keyue Ding, Ph.D., and Laurence Klotz, M.D.: Intermittent Androgen Suppression for Rising PSA Level after Radiotherapy Since Huggins and Hodges’s function of 19411 showing the androgen dependence of prostate malignancy, androgen deprivation has been the mainstay treatment for metastatic disease.Insomnia may be the most reported sleep disorder commonly. About 30 % of adults have symptoms of insomnia. It is suggested that adults get between seven and eight hours of nightly rest. The American Academy of Sleep Medicine offers the following tips about how to get a good night’s rest: Follow a consistent bedtime routine. Set up a relaxing setting at bedtime. Get yourself a full night’s sleep every night. Avoid drinks or foods that contain caffeine, in addition to any medicine which has a stimulant, to bedtime prior. Usually do not bring your concerns to bed with you. Do not go to bed hungry, but don’t eat a big meal before bedtime either. Avoid any rigorous workout within six hours of your bedtime. Make your bedroom silent, dark and a little bit cool. Get up simultaneously every morning.