In previous literature, there has been more of a definitive picture of blacks without diabetes, but here we demonstrated that APOL1 gene variants also are likely involved in the advancement of kidney failure in those with diabetes. Such details helps researchers better understand why African-Americans are four times more likely to develop kidney failure than whites, regardless of the cause of failure. Related StoriesScalable production of gene therapy vectors: an interview with Frank UbagsApoE4-carrying males with Alzheimer's disease at risk of mind bleedsPerisylvian polymicrogyria gene found It also helps explain, in part, the faster progression toward kidney failure observed in blacks with CKD, she added.Results of medical procedures and radiation therapy for vestibular schwannomas connected with neurofibromatosis type 2 are worse than for sporadic tumors, because prices of tumor control are iatrogenic and reduced hearing loss is more frequent. 4-6 Even though morbidity of active treatment can be high prohibitively, the results of unchecked tumor development are also severe. Presently, no procedures for tumors connected with neurofibromatosis type 2 can be found, and a effective and safe treatment for these individuals is needed. Vascular endothelial growth factor is a crucial mediator of tumor angiogenesis and vessel permeability.7-9 VEGF and its own receptor VEGFR-1 have already been detected in schwannomas, and increased degrees of these factors correlate with an increase of rates of tumor growth.15 The VEGF-neutralizing antibody bevacizumab has been approved by the Food and Drug Administration for use in the treating cancers, but simply no scholarly studies have been performed in sufferers with neurofibromatosis type 2 or vestibular schwannomas.