Stapled Peptides are a new course of drugs with a unique set of properties that completely capitalize on 25 years of genetic study to attack drivers of complex diseases, including cancer, endocrine/metabolic disorders and inflammation. The Stapled Peptide system locks peptides into their biologically active form and imparts pharmaceutical balance within the body. Stapled Peptide drugs, like ATSP-9172, are derived from natural peptides and so are designed to potently and particularly target protein-protein interactions both outside and inside the cell. This new class of drugs represents a simple scientific breakthrough as they offer the innovative way to modulate signaling pathways to take care of human disease..The research, published Sept. 4 in the open-source journal Cell Reports, could have essential implications for delaying ageing and disease in human beings, said David Walker, a co-employee professor of integrative biology and physiology at UCLA and senior writer of the research. ‘We’ve shown that whenever we activate the gene in the intestine or the nervous system, we see the aging procedure can be slowed beyond the organ system where the gene is usually activated,’ Walker said.